Calico is a coat pattern rather than a breed: white with patches of black and orange, or soft gray and cream in the dilute version. The pattern appears on domestic shorthairs and longhairs and on several pedigreed breeds. Nearly all calicos are female, because the orange and black colors are carried on the X chromosome.
In Albuquerque, most calicos are ordinary domestic cats, so size, coat and health follow the typical house cat: usually 6 to 12 pounds, living 12 to 18 years. Folklore calls calicos sassy, but coat color hasn't been shown to predict personality, so how a cat behaves with people and other pets tells you more. Shedding is moderate, and regular brushing helps keep a coat comfortable in the dry high-desert air.